FTD biomarker

2021: blood-based measurement of the glial fibrillary acidic protein (GFAP) can distinguish FTD from primary psychiatric disorders. levels in those with FTD were higher compared to persons with psychiatric disorders and persons without health ailments. An Abbott i-STAT device can be used to instantly measure GFAP.

Tauopathy proof

Sep 2018: There is currently no established clinical test that can reliably identify FTLD-Tau antemortem and autopsy-confirmed studies are rare.

June 2019: At this time, T-tau, but not p-tau, can be reliably measured in plasma using ultra-sensitive immunoassays.

Microinfarcts may be the second most important cause of dementia.

Alogia  – poverty of speech, is a general lack of additional, unprompted content seen in normal speech.

Apathy  lack of interest in personal

Avolition describes an inability to initiate tasks or see them through, which causes the patient to avoid activities and spend long periods of time doing nothing.

Anhedonia – a diminished capacity to experience pleasant emotions

Eye marker

FTD outer retina thinning persists and longitudinally correlates with disease progression. These findings were especially seen in probable tauopathy patients, which showed progressive outer retina thinning. Using a spectral-domain optical coherence tomography SD-OCT.